chemotherapy
A commonly used therapy to treat cancer with is chemotherapy. The agents in chemotherapy circulate through the body and can target fast dividing cancerous cells almost anywhere in the body, this is known as systemic treatment. A consequence of this systemic approach is that healthy cells which are also in their cell replication process (mitosis), like gut bacteria, will also be targeted. Therefore, unfortunately chemotherapy leads to several side effects, with gastrointestinal mucositis, translocation of bacteria and microbiome changes being one of the most frequent. Several studies have confirmed that chemotherapy is linked to reduced microbiome diversity and also changes in metabolic activity.
Luckily there is bactoyou, offering aid to overcome the side effects of chemotherapy. By re-introducing a past captured microbiome, a bac-up, before undergoing a chemotherapy treatment, you can make sure to maintain a diverse microbiome.
Touchefeu, Y., E. Montassier, K. Nieman, T. Gastinne, G. Potel, S. Bruley Des Varannes, F. Le Vacon, and M. F. De La Cochetière. "Systematic Review: The Role of the Gut Microbiota in Chemotherapy- or Radiation-induced Gastrointestinal Mucositis - Current Evidence and Potential Clinical Applications." Alimentary Pharmacology & Therapeutics, 2014. doi:10.1111/apt.12878.
D. Rothschild et al., “Environment dominates over host genetics in shaping human gut microbiota,” Nature, doi:10.1038/nature25973, 2018.
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Montassier, Emmanuel, Eric Batard, Sébastien Massart, Thomas Gastinne, Thomas Carton, Jocelyne Caillon, Sophie Le Fresne, Nathalie Caroff, Jean Benoit Hardouin, Philippe Moreau, Gilles Potel, Françoise Le Vacon, and Marie France De La Cochetière. "16S RRNA Gene Pyrosequencing Reveals Shift in Patient Faecal Microbiota During High-Dose Chemotherapy as Conditioning Regimen for Bone Marrow Transplantation." Microbial Ecology 67, no. 3 (2014): 690-99. doi:10.1007/s00248-013-0355-4.
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Montassier, E., T. Gastinne, P. Vangay, G. A. Al-Ghalith, S. Bruley Des Varannes, S. Massart, P. Moreau, G. Potel, M. F. De La Cochetière, E. Batard, and D. Knights. "Chemotherapy-driven Dysbiosis in the Intestinal Microbiome." Alimentary Pharmacology & Therapeutics 42, no. 5 (2015): 515-28. doi:10.1111/apt.13302.